Splice summary and reviews

Splice synopsis, summary and reviews

5.9
5.9 star

Splice (2010) Movie Summary

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  • HORROR
  • SCIENCE FICTION
  • R
  • 2010
  • FULL HD

Superstar genetic engineers Clive (Adrien Brody) and Elsa (Sarah Polley) specialize in splicing DNA from different animals to create incredible new hybrids. Now they want to use human DNA in a hybrid that could revolutionize science and medicine. But when the pharmaceutical company that funds their research forbids it, Clive and Elsa secretly take their boldest experimentation underground--risking their careers by pushing the boundaries of science to serve their own curiosity and ambition. The result is Dren, an amazing, strangely beautiful creature of uncommon intelligence and an array of unexpected physical developments. At first, Dren exceeds their wildest dreams. But as she grows and learns at an accelerated rate, her existence threatens to become their worst nightmare.

Splice Film Synopsis

Elsa and Clive, two young rebellious scientists, defy legal and ethical boundaries and forge ahead with a dangerous experiment: splicing together human and animal DNA to create a new organism. Named "Dren", the creature rapidly develops from a deformed female infant into a beautiful but dangerous winged human-chimera, who forges a bond with both of her creators - only to have that bond turn deadly.

Splice Comments & Critics

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Splice Movie Reviews

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Ugh! Another alien/species/king long ripoff!What was more disturbing? The creature itself or watching the characters make all the wrong choices. I was hoping they would be written with a lot more common sense!.Score: 2/5

No me gustaNo me gustan estas peliculas aqui en itunes,aparte de ser muy caras,solo en ingles entan,vaya porqueria.Score: 1/5

I agree, this is bad!I have to chime in the the one star rating. I saw this in the theater and stayed only to see how bad it could get. This will go down as one of the worst sci-fi movies ever. ***Spoiler*** What is up with the boyfriend having sex with the human-creature hybrid? And the creature turning female and raping the female scientist, who then agrees to have the resulting baby? I've never sat through more awkward and horrifying moments in a movie. Wow... someone should have read the script before making this movie, but then I'm not surprised that Hollywood thought the story was a good idea..Score: 1/5

Could have, but flopsCannot recommend it. Very good cinematography. Ok directing, almost nice script. Nice acting by all, except the "spliced" girl. She was extremely amateurish and unrehearsed. Most of her scenes should have been reshot. Is she the director's girlfriend, or something?.Score: 2/5

Great Sci-Fi movie!That some people want Bambi and will rate this work low is astonishing. Looking at the name & completely naked Dren on the Movie's "Poster / box cover. Then have the gall to be shocked when sex happened and horror happened. How hypocritical :) I must say some who were offended completely Internalized every scene with Dren and it says alot about human psychology. They were used to seeing themselves in a herione's place. And when they followed their normal fantasy it backfired on them. Ouchies. I'm not insensitive, I'm just saying that if you watch a "HORROR" movie and are horrified, I'd say the movie did it's job. My girlfriend is such a one. She was openly horrified by "That Scene" while I had one of the biggest laughs of my life when the "Door Opened". Again great original take on a classic Horror movie..Score: 5/5

Not your average horror movieThis movie is not for everyone, and it revels in that position. This isn't a standard sort of horror movie, this is psychological horror. The downward spiral of events as they become more and more morally apprehensive, the ending, all to make the watcher as uncomfortable as possible. It doesn't scare you, it causes psychological damage that most horror films don't even come close to..Score: 5/5

Love this movieIt's wired and scary all at the same time. But in a good way. It's not "scary" to me at all, but when it killed the cat I kinda freaked out. Haha but I love this movie. But if u aren't in to scary and awkward movies then don't watch..Score: 5/5

Awkward & twisted - Not even worth rentingThe story line was interesting the first 1/2 of the film. About 3/4 of the way in it just started going down hill and by the last 1/4th it totally went off the rails and was just trying for shock value. I got to see an early screening of this and was so glad that I didn't pay the price of admission. It was by far one of the worst science fiction/ horror flicks I've ever seen. Don't waste your money or your time. It's not even a rental..Score: 1/5

I actually liked itMaybe im just messed up in my head but i enjoyed the movie. i like it because movies like this dont really come out and if they do people look down on them. i loved it..Score: 5/5

The WorstI actually threw this DVD in the trash after watching it..Score: 1/5

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Splice (2010) Series Cast & Crew

Splice (2010) cast and crew credits, including actors, actresses, directors, writers and more. Adrien Brody (Clive), Sarah Polley (Elsa), Delphine Chanéac (Dren), David Hewlett (Barlow), Abigail Chu (Young Dren), Stephanie Baird (Elsa / PD), Brandon McGibbon (Gavin), Amanda Brugel (Melinda Finch), Simona Măicănescu (Joan Chorot), all returned for splice movie.

Adrien Brody (Clive)
Adrien BrodyCliveScore: 40.2
Sarah Polley (Elsa)
Sarah PolleyElsaScore: 19.6
Delphine Chanéac (Dren)
Delphine ChanéacDrenScore: 18.7
David Hewlett (Barlow)
David HewlettBarlowScore: 14.8
Abigail Chu (Young Dren)
Abigail ChuYoung DrenScore: 11.6
Brandon McGibbon (Gavin)
Brandon McGibbonGavinScore: 6.7
Amanda Brugel (Melinda Finch)
Amanda BrugelMelinda FinchScore: 14.5
coursera

Guillermo del Toro (Producer), Steven Hoban (Producer), Antoinette Terry Bryant (Screenplay), Vincenzo Natali (Screenplay), John Buchan (Casting), Todd Cherniawsky (Production Design), Constance Demontoy (Casting), Joshu de Cartier (Art Direction), Doug Taylor (Screenplay), Jason Knight (Casting), Alex Kavanagh (Costume Design), Marie Nardella (Makeup Department Head), Vincenzo Natali (Director), David McCallum (Supervising Sound Editor), Roderick Deogrades (Sound Effects Editor), Rossana DeCampo (Scenic Artist), Garrett Kerr (Sound Effects Editor), Stefan Fraticelli (Foley), Lisa Burling (Script Supervisor), Sam Hudecki (Assistant Art Director),

Guillermo del Toro (Producer)
Guillermo del ToroProducerScore: 22.1
Steven Hoban (Producer)
Steven HobanProducerScore: 4.3
Vincenzo Natali (Screenplay)
Vincenzo NataliScreenplayScore: 6.8
John Buchan (Casting)
John BuchanCastingScore: 6.4
Jason Knight (Casting)
Jason KnightCastingScore: 5.7
Vincenzo Natali (Director)
Vincenzo NataliDirectorScore: 6.8
Men’s T-Shirts

Splice Trailers & Teasers

'Splice' Official Trailer (HD). First teaser trailer of splice, the Vincenzo Natali's popular movie. Watch the splice teaser trailer. Vincenzo Natali’s #splice is now on 4K UHD, Blu-ray and digital platforms.

Splice [Trailer 1] [HD] 2010▶ Splice [Trailer 1] [HD] 2010

Splice Screencaps, Images & Pictures

Check out photos from splice movie. Splice (2010) 1920x1080 HD wallpapers and high quality background images. Tons of awesome splice wallpapers to download for free.

SPLICE IMAGE EXPERIMENT IMAGE GENETICS IMAGE GENE MANIPULATION IMAGE DNA IMAGE GENETIC ENGINEERING IMAGE GENETICALLY MODIFIED ORGANISM IMAGE
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Splice Movie Screencaps, Images & Pictures

She's not human...not entirely...

Splice — 2010

Splice Posters

All released movie posters so far for the movie splice - 2010. A poster for Vincenzo Natali horror movie, Splice! High resolution official theatrical movie poster (#1 of 10) for splice (2010). Image dimensions: 2025 x 3000.

SPLICE POSTER GENETIC ENGINEERING POSTER GENETICS POSTER EXPERIMENT POSTER DNA POSTER GENETICALLY MODIFIED ORGANISM POSTER GENE MANIPULATION POSTER
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Splice Movie Posters
Brain Force

Splice Movie Languages & Subtitles

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Pусский
Двое ученых, Эльза и Клайв, пренебрегая морально-этическими категориями и уголовным кодексом, синтезировали ДНК человека и животного. В результате эксперимента на свет появилась девочка, впоследствии ставшая женщиной-химерой. С ней у создателей обнаруживается особая связь, грозящая им смертельной опасностью.

Français
Clive et Elsa sont des superstars de la science : ils ont réussi à combiner l'ADN de différentes espèces animales pour obtenir de fantastiques hybrides. Ils sont amoureux l'un de l'autre autant que de leur travail et veulent à présent passer à l'étape suivante : fusionner de l'ADN animal et de l'ADN humain.Lorsque le laboratoire pharmaceutique qui les finance refuse de les soutenir, Clive et Elsa décident de poursuivre leurs expériences en secret. Ils créent Dren, une créature étonnante dont la croissance rapide la fait devenir adulte en quelques mois. Alors qu'ils redoublent d'efforts pour préserver leur secret, leur intérêt scientifique pour Dren se mue peu à peu en attachement. Dren finira par dépasser les rêves les plus fous du couple... et leurs pires cauchemars.

Deutsch
Das Forscher-Paar Clive und Elsa leistet bei der Züchtung von Tier-Hybriden Pionierarbeit. Als ihnen der Geldhahn abgedreht wird, arbeiten sie trotzdem heimlich weiter und erschaffen in ihrem Labor eine Kreuzung aus Mensch und Tier. Clive sieht das Kaulquappen-ähnliche Wesen als Fehlschlag, will es töten, doch in Elsa erwachen Mutterinstinkte. So wächst Dren bei ihnen fast wie das Kind einer Familie auf. Doch wird es immer schwieriger sie zu verstecken und als sie geschlechtsreif wird, wird sie zu einer Gefahr für alle.

Italiano
Elsa e Clive, due scienziati giovani e ribelli, sfidano le norme dell'etica scientifica con il loro audace esperimento: combinare DNA umano e animale per creare un nuovo tipo di organismo vivente. Chiamata Dren dai suoi 'genitori', la creatura, un ibrido straordinario, cresce rapidamente fino a diventare prevedibilmente pericolosa. Dopo poco tempo quella che sembrava essere una scoperta in grado di rivoluzionare il mondo della scienza si rivelerà il più grande errore mai commesso.

Magyar
Clive és Elsa sztártudósok, akik hírnevüket annak köszönhetik, hogy különböző állatok DNS-ével bizarr hibrideket hoztak létre. Nemcsak munkájukban alkotnak párt, az életben is. Kutatóként legfőbb céljuk egy emberi hibrid előállítása lenne, de a munkájukat eddig finanszírozó vállalat ezt már nem támogatja, ezért úgy döntenek, titokban folytatják kísérleteiket. Létrehoznak egy különleges lényt, akit Drennek neveznek el. A hibrid gyors életciklusa révén hónapok alatt csecsemőből felnőtté válik. Miközben a két tudós mindenáron igyekszik leplezni a titkot, teremtményük kísérleti alanyból személlyé válik, sőt, képességeivel túlhaladja legmerészebb álmaikat. Hamarosan pedig a legijesztőbb rémálmaikat is.

Português
Clive e Elsa são dois brilhantes cientistas especializados na combinação de DNA e se dedicam a criar espécies híbridas de animais para um laboratório farmacêutico. Depois do sucesso de seu ultimo experimento, decidem em segredo dar um passo mais adiante e usar DNA humano para a criação de um novo ser que os ajude a revolucionar a medicina moderna. Mas a espécie resultante é muito mais que uma nova escala na árvore evolutiva: uma surpreendente criatura que excede seus sonhos mais ambiciosos.

Türkçe
Clive ve Elsa bilim dünyasının iki süper starıdır. Uzmanlık alanları DNA kopyalamak ve farklı canlıların DNA’larını birleştirerek hybrid yaratıklar yaratmaktır. Bilime olan aşkları da en az birbirlerine olan aşkları kadar güçlüdür. Ancak çalışmalarını artık bir adım daha ileriye taşımanın zamanı geldiğine inanmaktadırlar: insan DNA’sını kopyalamak.

svenska
Guillermo del Toro-producerad Sci-fi-thriller, av Cube-regissören Vincenzo Natali med Sarah Polley, Adrien BrodySci-fi-thriller om två unga vetenskapsmän som spränger både lagens och etikens gränser i ett livsfarligt experiment: att sammanföra mänskligt och animaliskt DNA.

Nederlands
De twee vooruitstrevende wetenschappers Elsa Kast en Clive Nicoli experimenteren met dierlijk DNA en het lukt hen deze te verenigen. Het levert een mutant op die behulpzaam zou kunnen zijn bij het genezen van ziekten, maar hun project zal binnenkort worden stopgezet. Ze realiseren zich dat ze niet veel tijd meer hebben en beginnen op eigen houtje, zonder dat iemand er verder van weet, een experiment met dierlijk én menselijk DNA. Het resultaat is verbluffend, maar tegelijk ook zeer riskant...

Español
Clive (Adrien Brody) y Elsa (Sarah Polley) son dos brillantes científicos que, por medio de la ingeniería genética, se dedican a crear variaciones de especies conocidas. Aunque han alcanzado el éxito, su ambición les hará perder el control, cuando, en secreto, decidan llevar sus experimentos más allá de la moral. Combinando ADN humano en sus experimentos genéticos obtendrán un nuevo escalón en el árbol evolutivo actual.

普通话
  在大公司纽斯特德的支持下,生物科学家克里夫·尼科利(阿德里安·布洛迪 Adrien Brody 饰)和女友艾尔莎·卡斯特(萨拉·波莉 Sarah Polley 饰)进行基因重组的实验,并取得初步进展。然而由于资金和公众舆论等原因,纽斯特德高层决定中断对他们现有研究的支持。克里夫和艾尔莎不愿半途而废,于是偷偷展开实验。他们对基因进行优化重组,并混入了艾尔沙的一部分基因,终于孕育出一个相貌奇特的雌性怪物。  秉着科学家的道德和良知,克里夫执意要杀死怪物,而艾尔莎则全力保护,视若己出,并将其命名为卓伦。卓伦以飞快的速度成长,最终变成一位拥有独特美感的女孩(Delphine Chanéac 饰)。在这一过程中,克里夫和艾尔莎越陷越深……

Polski
Para ambitnych naukowców rzuca wyzwanie prawom natury, rozpoczynając w tajemnicy eksperyment, który polega na skrzyżowaniu ludzkiego i zwierzęcego DNA. Badacze są przekonani, że efektem ich działań będzie udoskonalona wersja człowieka. Jednak istota, którą powołują do życia, okazuje się śmiertelnym zagrożeniem nie tylko dla swoich stwórców, ale i całej ludzkości.

ελληνικά
Η Elsa και ο Clive, δύο νεαροί και επαναστατικοί επιστήμονες, αψηφούν τα νομικά και ηθικά όρια διεξάγοντας ένα εξαιρετικά επικίνδυνο πείραμα: χωρίς να έχουν την έγκριση της φαρμακευτικής εταιρίας που τους χρηματοδοτεί, αναμιγνύουν ανθρώπινο και ζωικό DNA προκειμένου να δημιουργήσουν ένα νέο οργανισμό. Το αποτέλεσμα ξεπερνά κάθε φαντασία. Το πλάσμα, ονόματι 'Dren', εξελίσσεται γρήγορα από ένα παραμορφωμένο θηλυκό βρέφος σε μια όμορφη αλλά επικίνδυνη φτερωτή ανθρωπόμορφη Χίμαιρα, που αναπτύσσει ισχυρούς δεσμούς με τους δημιουργούς της, οι οποίοι θεωρούν πως δημιούργησαν τον τέλειο οργανισμό, μέχρι τη στιγμή που το πείραμα τους μεταμορφώνεται σε απειλή για ολόκληρη την ανθρωπότητα.

Český
Genetičtí inženýři Elsa a Clive tajně provedou experiment, jehož výsledkem je kříženec člověka a zvířete. Je to úžasné a podivně krásné stvoření, které by mohlo v moderní medicíně způsobit revoluci, pokud ovšem předtím nezničí lidstvo. Clive (Adrien Brody) a Elsa (Sarah Polleyová) se specializují na propojování DNA různých zvířecích druhů a vytvářejí tak fantastické nové hybridy. Nyní se chystají k experimentu, jehož výsledek by mohl způsobit revoluci ve vědě a medicíně, hodlají totiž propojit zvířecí a lidskou DNA. Farmaceutická společnost, která jejich výzkum financuje, jim však experiment zakáže. To ale zvídavé genetické inženýry nemůže zastavit, Clive a Elsa se přesunou do podzemí a kvůli své ctižádostivosti riskují kariéru. Výsledkem experimentu je Dren, úžasné a podivně krásné stvoření, které je neobvykle inteligentní a nečekaně fyzicky vyvinuté.

Dansk
De to unge, rebelske forskere Clive (Adrien Brody) og Elsa (Sarah Polley) overtræder alle reglerne, da de under et uskyldigt eksperiment blander menneske DNA med DNA fra flere forskellige dyr. Ganske uforsætligt producerer dette et helt nyt væsen, der hurtigt vokser sig stort og meget farligt.

עִבְרִית
אלסה וקלייב הם שני מדענים מורדים אשר חוצים את גבולות החוק והאתיקה על מנת לקחת חלק בניסוי מסוכן - חיבור בין גנים אנושיים לאלה של בעל-חיים על מנת ליצור יצור יוצא דופן בשם "דרן". אותו יצור הופך מגולם מעוות לבחורה יפהפייה אך מסוכנת מאוד, אשר יוצרת קשר עמוק בינה לבין יוצריה אבל קשר הטומן בחובו זרעי פורענות.

Português
Clive Nicoli (Adrien Brody) e Elsa Kast (Sarah Polley) ficaram famosos no meio científico pelas suas experiências na combinação do DNA de vários animais, gerando criaturas bizarras. Eles são apaixonados, tanto pelo trabalho que fazem quanto um pelo outro. Agora eles querem dar um passo adiante e combinar o DNA de animais com o de seres humanos, só que seus financiadores vetam a ideia. Eles seguem adiante com a iniciativa, em segredo. O resultado desta experiência é Dren (Delphine Chanéac), um ser cujo ciclo de vida extremamente rápido faz com que atinja a fase adulta em questão de meses. Clive e Elsa tentam manter Dren em segredo, mas logo a ligação entre eles deixa de ser meramente científica para se tornar pessoal.

Український
Двоє учених, Ельза і Клайв, незважаючи на морально-етичні норми і кримінальний кодекс, синтезували ДНК людини і тварини. В результаті експерименту на світ з'явилася дівчинка, що згодом стала жінкою-химерою. З нею у творців виявляється особливий зв'язок, що загрожує їм смертельною небезпекою.

Français
Clive et Elsa sont des superstars de la science : ils ont réussi à combiner l'ADN de différentes espèces animales pour obtenir de fantastiques hybrides. Ils sont amoureux l'un de l'autre autant que de leur travail et veulent à présent passer à l'étape suivante : fusionner de l'ADN animal et de l'ADN humain.Lorsque le laboratoire pharmaceutique qui les finance refuse de les soutenir, Clive et Elsa décident de poursuivre leurs expériences en secret. Ils créent Dren, une créature étonnante dont la croissance rapide la fait devenir adulte en quelques mois. Alors qu'ils redoublent d'efforts pour préserver leur secret, leur intérêt scientifique pour Dren se mue peu à peu en attachement. Dren finira par dépasser les rêves les plus fous du couple... et leurs pires cauchemars.

普通话
一對科學家情侶將人的DNA加入他們的動物基因拼接工作中。

Español
Elsa y Clive, dos jóvenes científicos rebeldes, desafían los límites legales y éticos y avanzan con un experimento peligroso: empalmar el ADN humano y animal para crear un nuevo organismo. Nombrada "Dren", la criatura se desarrolla rápidamente a partir de un infante femenino deformado en una bella pero peligrosa humana-quimera alada, que forja un vínculo con sus dos creadores - sólo para que el enlace se vuelva mortal.

한국어/조선말
전도 유명한 과학자 커플 ‘클라이브’(애드리안 브로디)와 ‘엘사’(사라 폴리)는 난치병 치료용 단백질을 만드는 연구를 진행하던 중, 조류, 어류, 파충류, 갑각류 등의 다종(多種) DNA 결합체인 ‘프레드’ 와 ‘진저’를 탄생시켜 동물용 의약 단백질 생산을 가능케 한다.실험을 거듭하면서 유전자 재조합 기술은 발전하고, 다종 DNA 결합체와 인간 유전자의 결합이 가능한 수준에 이르자 과학계와 의학계에 놀라움을 선사하고 싶었던 두 커플은 위험한 실험을 시도한다. 제약회사의 경고에도 불구하고 다종의 결합체와 인간 여성의 DNA를 결합시키는 금기의 실험을 강행하여 인간도, 동물도 아닌 전혀 새로운 생명체인 ‘드렌’을 탄생시킨다. 단순한 생명체의 형태에서 빠른 세포분열을 일으키며 급속도로 성장한 드렌은 각 종(種)들의 특징을 드러내며 기이한 아름다움을 내뿜고, 마침내 인간의 ‘감정’까지 갖추게 되면서 본능적으로 이성인 클라이브와의 교감을 시도한다. 그러나 그녀는 일정기간이 지나면 성(性)의 전환을 이루는 특성을 가지고 있었고 누구도 예상하지 못했던 그녀의 변이는 치명적인 결말을 예고하는데…… 줄거리 2. 새로운 종을 탄생시켜 의학계와 과학계는 물론, 세상을 놀라게 만들 경이로움을 선사하고 싶었던 과학자 부부 ‘클리브’(애드리안 브로디)와 ‘엘사’(사라 폴리). 제약회사의 경고에도 불구하고 인간 여성의 DNA와 조류, 어류, 파충류, 갑각류의 유전자를 결합하는 금기의 실험을 강행해 신 생명체인 ‘드렌’을 탄생시킨다. 빠른 세포분열을 일으키며 급속도로 성장한 드렌은 각 종(種)들의 특징을 드러내며 기이한 아름다움을 내뿜고, 마침내 인간의 ‘감정’까지 갖추게 되면서 본능적으로 이성인 클리브와의 교감을 시도한다. 그러나 그녀는 일정기간이 지나면 성(性)의 전환을 이루는 특성을 가지고 있었고 누구도 예상하지 못했던 그녀의 변이는 치명적인 결말을 예고하는데…

العربية
تتناول احداث الفيلم حول كليف واليسا الذين قاما بمزج جينات لحيوان كانا يقوما باجراء التجارب عليه بجينات اخري لانسان ونتج عن ذلك كائن حول الحياة لجحيم .

Latviešu
Jauns solis šausmu un zinātniskās fantastikas filmu attīstībā - „Himera". Divi zinātnieki nolemj ignorēt morāles normas un veikt vēl nebijušu un bīstamu eksperimentu. Viņi savieno cilvēka un vairāku dzīvnieku ģenētiskos kodus un rada pavisam jaunas sugas organismu. Viņi dod tai vārdu - Drena. Drena attīstās ļoti ātri, līdz kļūst par skaistu, bet ļoti bīstamu himeru. Viņas attiecības ar saviem radītājiem šķiet stipras un skaistas, taču līdz kādam brīdim...

български език
Клайв (Ейдриън Броуди) и Елза (Сара Поли) са млади и амбициозни учени, които се опитват да влязат в историята като изградят ново стъпало в еволюцията, игнорирайки моралните и законните граници на обществото си. Двамата съединяват ДНК от различни животни с човешка, като резултатът наричат "Дрен". Първоначално съществото прилича на деформирано женско бебе, но бързо се развива. Клайв и Елза са доволни и смятат, че са създали съвършения организъм, докато не видят последната метаморфоза (красива и крилата Химера), заплашваща животът им... и този на останалото човечество.

普通话
佳夫(艾哲倫保迪 飾)和艾莎(莎拉寶莉飾)是科學界的大明星,精於把不同的動物基因結合起來,創造新的動物品種。兩人深愛對方、熱愛工作,打算再進一步,將人類基因和動物基因結合起來,可是遭到資助企業的拒絕。二人決定秘密進行實驗,創製全新品種的人獸合體,並把她命名為DREN。DREN自製成後,迅速在幾個月內從嬰兒化身為成人。佳夫和艾莎只好盡力把DREN隱藏,過程間,二人對DREN產生了個人情感,而不再只視她為一件科學實驗品。可是,DREN的成長卻超出了他們的預期,令他們陷入比惡夢更可怕的環境之中。

suomi
Työn ja rakkauden yhdistämät nuoret ja huippulahjakkaat geenibiologit Elsa Kast ja Clive Nicoli kuohuttavat tiedemaailmaa rajoja rikkovilla keksinnöillään. He onnistuvat luomaan uusia hybridilajeja eläinten DNA:ta manipuloimalla. Seuraava looginen askel olisi yhdistää ihmisen ja eläinten perimää: tulos olisi arvatenkin mullistava. Sekä tiedeyhteisö että Elsan ja Cliven tutkimusta tukenut lääkeyhtiö pitävät ajatusta liian radikaalina ja eettisesti arveluttavana. Kielloista huolimatta he jatkavat kokeilujaan suljettujen ovien takana ja onnistuvat luomaan olion, joka on osaksi ihminen, osaksi eläin - älykäs ja elinvoimainen. Paljastumisen pelossa pariskunta joutuu kuljettamaan Drenin pois laboratorion turvasta. Kaunis ja virtaviivainen olio, jota kumpikin on oppinut tavallaan rakastamaan, saa piilotella epämukavissa oloissa Elsan äidin maatilalla. Seuraa joukko raadollisia tapahtumia, jotka kääntävät kolmikon valtasuhteet nurinniskoin. Ihmisten hirviöpuoli alkaa päästä esiin.

Slovenčina
Clive a Elsa sa špecializujú na prepájanie DNA rôznych zvieracích druhov a vytvárajú tak fantastické nové hybridy. Teraz sa chystajú vykonať experiment, ktorý by mohol spôsobiť revolúciu vo svete vedy a medicíny. Majú v pláne spojiť ľudskú a zvieraciu DNA. Farmaceutická spoločnosť, ktorá ich výskum financuje, im však experiment zakáže. To ale zvedavých genetických inžinierov nezastaví. Clive a Elsa sa presunú do podzemia a pre svoju ctižiadostivosť riskujú kariéru. Výsledkom experimentu sa stane Dren, úžasné a podivné stvorenie, ktoré je neobvykle inteligentné a nečakane fyzicky vyvinuté. Rastie však veľmi rýchlo a jeho existencia sa čoskoro stane ich najhoršou nočnou morou.

Română
Clive (Adrien Brody) și Elsa (Sarah Polley) sunt adevărate superstaruri în lumea experimentelor genetice. Cei doi și-au câștigat faima combinând ADN-ul provenit de la specii diferite de animale pentru a crea hibrizi bizari. Se iubesc unul pe celălalt la fel de mult precum își iubesc munca. Dar acum vor să treacă la nivelul următor al carierei lor, dar, poate, și al evoluției: să combine ADN uman cu ADN animal. Când li se refuză finanțarea, cei doi continuă experimentul în secret. Rezultatul este Dren (Delphine Chaneac): o creatură mai mult decât ciudată, o femelă parte om, parte animal, care se transformă dintr-un bebeluș în adult în doar câteva luni. Clive și Elsa se luptă să o țină ascunsă pe Dren, însă ceea ce aduce această creatură în viața lor va depăși cele mai îndrăznețe visuri ale lor, dar și cele mai înfiorătoare coșmaruri.

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